Diabetes: When the body stops making insulin or stops reponding to it, it can no longer process sugars in the blood efficiently. The kidneys will release sugar into the Cavalier King Charles Spaniel's (dog's) urine, which makes her urinate more and have to drink more. The primary symptoms of diabetes are excessive drinking and urination, sometimes accompanied by weight loss despite increased appetite, or blindness or numb limbs. Treatment is available, and early detection is crucial.